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Once improved definition of these mechanisms are established, the next step should involve targeted interventions

Amelioration of degenerative phenotypes in park 13 dopaminergic neurons Oxidative stress is one of the major underlying causes of sporadic and familial forms of Parkinsons disease and mainly characterized by an imbalanced GSH/GSSG cycle, enhancing cellular susceptibility to oxidation 37

Oxidative DNA damage results in mutations that generate dysfunctional protein gene products and altered replication and transcription of crucial genes (44, 5355)

doi: 10.1152/physrev.00023.2017 49 SunXOuZChenRNiuXChenDKangRet al

not FDA-approved and used only in a research context

Pattern of expression of toll like receptor (Tlr)-3 and -4 genes in drug-nave and antipsychotic treated patients diagnosed with schizophrenia